Thealoz® Duo

First Combination for Ocular Surface Bioprotection

Thealoz® Duo is the first combination drop of Sodium Hyaluronate and Trehalose that goes beyond hydration to offer patients ocular surface bioprotection.

Drop Features:

The synergistic action of both Trehalose and Hyaluronic Acid helps target different entries of the vicious circle and:

  • Reduces inflammatory biomarkers in the tear film1
  • Increases Goblet Cell density and reduces the epithelial metaplasia (29.8% increase in Goblet Cell density at 2 months)1
  • Significantly decreases ocular surface damage in dry eye patients1
  • Can be used with all types of contact lenses

Ideal for Patients:

  • All dry eye patients when symptoms arise
  • People looking for lasting relief that protects the eye’s surface and soothes symptoms
  • Day and nighttime use (particularity suited for day use in combination with Thealoz Duo Gel drops during the evening)

Thealoz® Duo is uniquely formulated containing:

  • Hyaluronic Acid – Hydrates and lubricates the corneal surface
  • Trehalose – A natural disaccharide synthesized by plants, such as the Rose of Jericho, as a response to stress (dryness, osmopressure, freezing)2

Trehalose also protects corneal cells against ultraviolet (UV) – induced oxidative damage3

Mechanism of Action

  • Bioprotection4 is a mechanism that helps preserve the cell structure, stabilize membrane lipids, protect proteins, and induce autophagy. All of these properties lead to a decrease in cellular apoptosis.
  • Osmoprotection5 allows the balance of osmotic pressure on both sides of the cell membrane, stabilizes the membrane lipids, and protects proteins
  • Regeneration3,6 renews cell material by inducing autophagy

Did you know?

Hypotonic hyaluronic acid reduces dry eye symptoms more effectively than isotonic hyaluronic acid7

Format:  ABAK Bottle Delivery System

Efficient, precise and easy to use

  • Provides 300 drops
  • Bottle remains sterile and can be used up to 3 months after opening
  • Easy to apply, precise

Thea is a pioneer and world leading manufacturer of preservative-free eye care packaging technology.

  • First ABAK bottle created in 1989
  • One bottle is sold every 2 seconds across the world
  • Eco- friendly and ergonomic- keeping patients in mind during the development process
  • 10 years of research and 25 years of experience

Thealoz® Duo improved the following for patients over HA alone.  Patients can expect to see:

  • A greater improvement in Tear Film Thickness (TFT) (Up to 240 minutes)8
  • A greater improvement in OSDI scores (at Day 84)9
  • A greater improvement in global ocular symptoms and symptom severity scores (stinging, itching and blurred vision (at Day 35))9
  • Greater satisfaction on efficacy assessment scores9

Please note: The information contained on this page is intended for Canadian Healthcare Professionals